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Bioenzym 2G
Pharmacokinetics
Bioenzym 2G tablets feature a coating that prevents them from dissolving in the gastric tract; instead, their main active ingredients are released in the intestinal tract. Once released, the main active ingredients pass into the bloodstream through the chyliferous membranes. The following ranges of absorption have been verified: bromelain 39%; pancreatin 19%; papain 7%; trypsin 28%. Once absorbed, the enzymes combine with the antiproteases alpha-1 antitrypsin and alpha-2 macroglobulin, thereby preventing the patient's immune system from recognizing the enzymes as antigens, without this meaning that enzyme activity is inhibited. In fact, these antiprotease-enzyme complexes have proven pharmacological activity. The enzymes absorbed are eliminated hepatically or through the mononuclear phagocyte system. In some studies, it is also assumed that the enzymes absorbed could be eliminated through the pancreatic juice.
